Dr. György T. Balogh

Publications

1. Gyarmati, Benjámin ; Dargó, Gergő ; Szilágyi, Barnabás Áron ; Vincze, Anna ; Facskó, Réka ; Budai-Szűcs, Mária ; Kiss, Eszter L. ; Szente, Lajos ; Szilágyi, András✉; Balogh, György T.✉ Synthesis, complex formation and corneal permeation of cyclodextrin-modified, thiolated poly(aspartic acid) as self-gelling formulation of dexamethasone. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 174 pp. 1-9. , 9 p. (2022)
https://doi.org/10.1016/j.ejpb.2022.03.008
2. Vincze, Anna ; Dargó, Gergő ; Rácz, Anita ✉ ; Balogh, György T. ✉: A corneal-PAMPA-based in silico model for predicting corneal permeability. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 203 p. 114218 Paper: 114218, 10 p. (2021)
https://doi.org/10.1016/j.jpba.2021.114218
3. Dargó, G; Bajusz, D; Simon, K; Müller, J; Balogh, GyT✉: Human serum albumin binding in a vial: a novel UV-pH titration method to assist drug design. JOURNAL OF MEDICINAL CHEMISTRY 63(4) pp. 1763-1774. (2020)
https://doi.org/10.1021/acs.jmedchem.0c00046
4. Balogh-Weiser, D; Decsi, B; Krammer, R; Dargó, G; Ender, F; Mizsei, J; Berkecz, R; Gyarmati, B; Szilágyi, A; Tőtős, R; Paizs, Cs; Poppe, L; Balogh, GyT✉: Magnetic Nanoparticles with Dual Surface Functions—Efficient Carriers for Metalloporphyrin-Catalyzed Drug Metabolite Synthesis in Batch and Continuous-Flow Reactors. NANOMATERIALS 10 Papers 2329. (2020)
https://doi.org/10.3390/nano10122329
5. Fődi, T; Ignácz, G; Decsi, B; Béni, Z; Túrós, Gy I; Kupai, J; Balogh-Weiser, D; Greiner I; Huszthy, P; Balogh GyT.✉: Biomimetic synthesis of drug metabolites in batch and continuous‐flow reactors. CHEMISTRY-A EUROPEAN JOURNAL 24 :37 pp. 9385-9392. (2018)
https://doi.org/10.1002/chem.201800892

Awards

2015 Márton Kajtár Award
2014 János Bolyai Research Fellowship: outstanding qualification, diploma of recognition
2011 BME VBK, honorary associate professor
2010 Richter Innovative Knowledge Base, RITA Award
2009 BME VBK, honorary lecturer
2005 Lajos Kisfaludy Foundation Award
1999 OTDK 1st place (Veszprém)
1998 TDK 1st place, Merck Award (BME VBK)

Projects

As a leading researcher:
2021– CELSA 2021/019, BME-KU-Leuven, Development of In silico Absorption Models by Machine Learning Method
2020– Cooperative Doctoral Program Application, NKFIH, 1010984, Chemical Library Planning in Pharmaceutical Research
2020– TKP-2020. NKA-05, Intensification of Chemical Technologies, Development of High Permeability Biometric Systems Subgroup
As a co-researcher:
2016–2021 OTKA K119770
2020– OTKA K134704

Conferences

Invited Lecturer

2022 PSCR (Osaka) Organ-on-a-chip - session chair
2021 Waters Corp., online Research Meeting: Opportunities for metalloporphyrin-based biomimetic drug metabolite synthesis and structure elucidation
2020 Work Group Meeting 3, Malta (CA 18238): Preliminary study for tissue specific (BBB,
heart and liver) permeability screening of specific marine actinomycetes extracts
2018 BME FEE Medical Engineering Open Day: Research and Development at Richter
2017 Babes-Bolyai University guest lecture: Physico-chemical characterization of drugs
2017– Carpathian Basin Chemistry Camp, Zenta: every year lectures on drug research are different
Hungarian high school students living in Serbia
2012 4th Balaton Course in Medicinal Chemistry, Balatonszemes: Investigation of drug metabolism in drug discovery
2012 PhysChem FORUM 12, Budapest: PAMPA based in vitro assay for drug-induced
phospholipidosis in the early stage of drug discovery
2011 Agilent Technologies - Kromat Kft. HPLC / MS seminar, Budapest: LC-TQ (SQ) MS techniques in early stage of drug discovery
2010 ChemAxon User Group Meeting, Budapest: Comparsion of pKa predictors on in-house data set.

Patents

1. Nagy, ZZs ;, Balogh, GyT; Katona, G; Csorba, A; Kiss, H; Zupkó, I; Csóka, I: Postoperative application of the ASP eye drop formula. Date: 2021
2. Balogh, GyT; Elijah, J; Boros, A; Forrai, E; Székely, Á: Pharmaceutical composition comprising the zinc-hyaluronate complex for the treatment of multiple sclerosis. WO 2005049047, Date: 2005

Other activities

Hungarian Society of Pharmaceutical Sciences (MGyT), member, 2013–
MGyT Pharmaceutical Research Department, board member, 2017–
MGyT Pharmaceutical Analytical Working Committee, Member of the Board, 2017–
Hungarian Society of Separation, member, 2010–
Hungarian Academy of Sciences, member of the public body, 2003–
Pharmaceutical Chemistry and Pharmaceutical Technology Working Committee of the Hungarian Academy of Sciences, voting member, 2003–
Heterocyclic and Organic Chemistry Working Committee of the Hungarian Academy of Sciences, member, 2008–
Association of Hungarian Chemists, member, 2003–2021