FirePharma Research Group
Research keywords:
· pharmaceutical technology
· process analytical technology
· artificial neural network
· flame retardancy
· biopolymers
Horizon Europe keywords:
· Advanced materials
· Artificial Intelligence and Robotics
· Green social innovations
· Pharmaceutical technologies
Introduction of the Research Group
The FirePharma research group researches health and environmentally friendly composites, biomaterials, pharmaceuticals and other multi-component systems, and develops innovative methods. The synthesis of new additives, the analysis and modification of the surface and interface layers, the applied technological and analytical tools provide the common background for these research areas. The theoretical and practical results of the research group have already led to results in many fields of materials science, on which the current research in the group is based. The main research areas of the current research team of 34 people include research on biopolymers and flame retardants, developments in pharmaceutical technology based on artificial intelligence and modeling, research related to continuous pharmaceutical manufacturing, and research to improve the dissolution of poorly water-soluble drugs. The research team is involved in several domestic and international collaborations in these areas.
Watch our 3-minute introductory video:
Achievements
- More than 450 publications.- Patents related to pharmaceutical applications and flame retardancy.
- National projects with the main players of the Hungarian pharmaceutical industry.
- Experience in international cooperation projects
- Supervising PhD students and undergraduate students.
- Active involvement in international student and staff exchange projects.
Publications
1. Zsombor K Nagy, Attila Balogh, Balázs Démuth, Hajnalka Pataki, Tamás Vigh, Bence Szabó, Kolos Molnár, Bence T Schmidt, Péter Horák, György Marosi, Geert Verreck, Ivo Van Assche, Marcus E Brewster: High speed electrospinning for scaled -up production of amorphous solid dispersion of itraconazole, 2015, https://doi.org/10.1016/j.ijpharm.2015.01.0252. Katalin Bocz, Beáta Szolnoki, Attila Marosi, Tamás Tábi, Maria Wladyka-Przybylak, György Marosi : Flax fiber reinforced PLA/TPS biocomposites flame retarded with multifunctional additive system, 2014, https://doi.org/10.1016/j.polymdegradstab.2013.10.025
3. Beáta Szolnoki, Katalin Bocz, Péter L Sóti, Brigitta Bodzay, Emese Zimonyi, Andrea Toldy, Bálint Morlin, Krzysztof Bujnowicz, Maria Wladyka-Przybylak, György Marosi: Development of natural fiber reinforced flame retarded epoxy resin composites, 2015, https: //doi.org/10.1016/j.polymdegradstab.2015.04.028
4. Brigitta Nagy, Attila Farkas, Martin Gyürkés, Szofia Komaromy-Hiller, Balázs Démuth, Bence Szabó, Dávid Nusser, Borbás Enikő, György Marosi, Kristóf Zsombor: In-line Raman spectroscopic monitoring and feedback control of a continuous twin-screw pharmaceutical powder blending and tableting process, 2017, https://doi.org/10.1016/j.ijpharm.2017.07.041
5. Hajnalka Pataki, Istvan Csontos, Zsombor K Nagy, Balazs Vajna, Milan Molnar, Laszlo Katona, Gyorgy Marosi: Implementation of Raman signal feedback to perform controlled crystallization of carvedilol, 2013, https://doi.org/10.1021/op300062t
Patents
- Fekete P., Nagy Zs.K., Marosi Gy. Coating preparation, Hungarian Intellectual Property Office, case number: P1100541 (2011) - Molnár K., Nagy Zs.K., Vas LM, Czigány T., Karger-Kocsis J., Marosi G., Electrostatic process and equipment for the production of nano- and microstructured functional coating of particles, Hungarian Intellectual Property Office, case number: P1200119 (2012) - Mihályfi Á, Helmajer L, Lovas Z, Bordácsné Bocz K, Ronkay F, Molnár B, Marosi G: Thermoplastic polyester and production process thereof, patent filed at: Hungarian Intellectual Property Office, patent number: WO 2022/112807. (2022) - Vadas D., Igricz T., Bocz K., Marosi G.: Poly(lactic acid)-based foam and manufacturing the same, Hungarian Intellectual Property Office, case number: P2000412 (2020, pending patent) - Záhonyi P., Domokos A., Nagy ZK, Szabó E.:Journals
- International Journal of Pharmaceutics,- European Journal of Pharmaceutics,
- Molecular Pharmaceutics,
- Polymer Degradation and Stability,
- Advanced Industrial and Engineering Polymer Research
Infrastructure
The FirePharma research group has several innovative facilities in the field of pharmaceutical technology such as electrospinning devices in different sizes, continuous blenders, continuous dryers and in-line applicable analytical tools (eg Raman spectroscopy and near infrared spectroscopy).Projects
2019-1.3.1- KK-2019-0 0 0 04 - 3 years, Funder: National Research, Development and Innovation Office2018–1.3.1-VKE-2018–0 0 017 - 3 years, Funder: National Research, Development and Innovation Office
2018-1.3.1-VKE-2018-00011 - 3 years, Funder: National Research, Development and Innovation Office
GINOP_PLUSZ-2.1.1-21-2022-00041 - 3 years, Funder: National Research, Development and Innovation Office
NVKP 16-1-2016-0012 - 3 years, Funder: National Research, Development and Innovation Office
Industry relations
- Richter Gedeon Plc.- Egis Pharmaceuticals Plc.
- PEMÜ Plastic Industry Plc.
- Pro-Form Ltd.
- EUROAPI Hungary Ltd.